Saturday, October 5, 2019
New York vs Belton Essay Example | Topics and Well Written Essays - 250 words
New York vs Belton - Essay Example Beltonâ⬠). The issue was that the police officer had arrested the men before searching and finding the drugs without a warrant to do so(ââ¬Å"New York v. Beltonâ⬠) In this case, the courts ruled that ââ¬Å"whenever the police arrest people in a car, they may search the passenger compartment without a warrantâ⬠(ââ¬Å"New York v. Beltonâ⬠). Additonally, it was made clear that police officers may search through a car and items in the car after an arrest. However, the courts made it clear that police officers needed to have ââ¬Å"good reasonâ⬠for searching the car without a warrant. This decision was written by Justice Potter Stewart on July 1, 1981(ââ¬Å"New York v. Beltonâ⬠). After the decision was made, trouble arose when three of the judges on the case decided that they did not agree with the ruling and dissented because they felt that the decision went too far in not protecting the right to privacy(ââ¬Å"New York v.
Friday, October 4, 2019
Cardiovascular Rehabilitation Essay Example | Topics and Well Written Essays - 2750 words
Cardiovascular Rehabilitation - Essay Example Despite available resources, unawareness and scarcity of professionals have led to limited access of such programmes. In this proposal, a programme has been proposed of cardiovascular rehabilitation that would not only incorporate exercise programmes, but also would educate patients in the line of lifestyle modification that involves unconventional approaches of imparting education at the time of deployment of rehabilitative programmes. A combination of dietary, psychosocial, medical, educational, rehabilitative, and behavioural modifications can go a long way to reduce cardiovascular risks so that morbidity and mortality of such patients would drastically reduce. Government guidelines and community agencies would serve to implement such a project in reality by ensuring active participation through mentoring of these patients so the national goal is achieved. Introduction: Improved prevention of coronary artery disease is one of the prime targets of the cardiovascular rehabilitation throughout the world. It is the key aim and central target of many Government bodies concerned with health of the people. These can be achieved by primary prevention, improved treatment of acute disease episodes, revascularization, and by secondary prevention. There is strong scientific and clinical evidence that coronary prevention through lifestyle measures, treatment of blood pressure, lipid control, aspirin therapy, post myocardial infarction treatment with beta blockers, statins, and angiotensin converting enzyme inhibitors, surgical revascularization have major roles to play in bringing the patients into acceptable life activities and perhaps to a risk-free tenure of livelihood for the rest of the life. This evidence applies to the patients with angina pectoris as well as post myocardial infarction, and those revascularized. Cardiovascular rehabilitatio n, however, is the key to these being achieved despite the complaint that it is not being used in its full potential. There are many factors involved in this affair. It is a known fact that full potential of these secondary prevention measures are not being realized in clinical practice, and as a result, the pace of progress in improving the effectiveness of secondary prevention is slow. There is failure to offer cardiac prevention and cardiovascular rehabilitation programmes to all patients at their first presentation with evidence or risks of coronary artery disease. Simply put, this fails to achieve and maintain risk factor modification and lifestyle adjustments with full use of cardiovascular rehabilitative measures. This proposal attempts to delineate a health promotion project from the point of view of cardiac rehabilitation considering the factors of demography, personnel support, economic support, and target population. There is, therefore, a need to establish and implement programmes that can be offered to all eligible patients. This will successfully recruit and retain patients and will achieve and maintain risk factor control through rehabilitative measures. This author will utilize knowledge of Cardiovascular Rehabilitation to establish effective cardiac preventio
Thursday, October 3, 2019
Developing A Performance Appraisal System Essay Example for Free
Developing A Performance Appraisal System Essay All organizations utilize some sort of system that periodically reviews the performance of every staff member. As the director of human resources, you are responsible for developing such a system. Write a 750- to 1,050-word paper in APA format that details an original performance appraisal system for a human service organization. Address the following: Determine the elements that should be present in an appraisal system. What is the purpose of a performance appraisal system and how does it benefit the organization? Outline the elements of good appraisal systems. Determine the criteria for each element that should be present in an appraisal system. Cite at least two sources. Determine the elements that should be present in an appraisal system The elements that should be present in an appraisal system are thorough goal-setting process, which decide what you want from employees and agree these objectives with them. The key component of the people element is the manager, who give your employees the tools, resources and training they need to perform well. The manager drives the system by setting expectations, communicating plans, encouraging development, and giving and receiving feedback. Carrying out the appraisal allow managers to monitor and assess employees performance, discuss those assessments with them and agree on future objectives .It also identifies employees developmental needs and includes robust reward and recognition practices. Consider pay awards and/or promotion based on the appraisal and decides how to tackle poor performance. However, there can be dangers as well as benefits of linking rewards to performance. What is the purpose of a performance appraisal system and how does it benefit the organization? The purpose of a performance appraisal system is the two basic systems operating in conjunction: an evaluation system and a feedback system. The main goal of the evaluation system is to recognize the performanceà gap (if any). This gap is the deficit that occurs when performance does not meet the standard set by the organization as adequate. The central aim of the feedback system is to notify the employee about the quality of his or her performance. Nonetheless, the information flow is not entirely one way. The appraisers also receive feedback from the employee about job problems, etc.) One of the best ways to appreciate the purposes of performance appraisal is to look at it from the different viewpoints of the main stakeholders: the employee and the organization. Outline the elements of good appraisal systems 1. Measurement vs. Management the performance measurement aspect of the performance appraisal system is a useful tool for measuring current productivity levels and determining the gap between those current levels and desired productivity levels. 2. Employee Input Employee input is a vital element of the effective performance appraisal system. It is essential for supervisors and managers to include the employee in the performance management process to ensure that the employee feels a sense of engagement in the process. 3. Clarification of Expectations Before a manager or supervisor can expect an employee to meet expectations, it is essential to ensure that the employees perception of what is expected is in alignment with the managers perceptions 4. Employee Development Perhaps the most essential element of an effective performance appraisal system is employee development. While the performance appraisal itself may identify areas where improvement is necessary, the employee development portion of the overall performance management system is used to determine the best way to bring this improvement to fruition. Determine the criteria for each element that should be present in an appraisal system There are four key elements in a good performance and appraisal system: Set objectives decide what you want from employees and agree these objectives with them. [ If appropriate, set timescales forà achieving them. ââ¬â Manage performance give your employees the tools, resources and training they need to perform well. If appropriate, set timescales for achieving objectives. ââ¬â Carry out the appraisal monitor and assess your employees performance, discuss those assessments with them and agree on future objectives. Provide rewards/remedies consider pay awards and/or promotion based on the appraisal and decide how to tackle poor performance. However, there can be dangers as well as benefits of linking rewards to performance.
Emerging Therapies for the Treatment of MS
Emerging Therapies for the Treatment of MS Currently, there are six new drugs that are being assessed by clinical scientists and some of these drugs have entered or completed phase 2 level and phase 3 level clinical trials. Three of these drugs are oral drugs and they include Lanquinimod, Teriflumomide and Di-methyl fumarate. The other three are monoclonal antibodies (mAb) namely Alemtuzumab, Daclizumab and Rituximab (Borrero et al, 2012). All of these drugs target the immune system in different ways but some of them still present with some side effects as well which are discussed below. Starting with Lanquinimod, it is an immunomodulator that is currently being trialled in patients with RRMS and SPMS. It has a very small recommended dose of 0.6 mg daily and it exhibits anti-inflammatory properties. These properties are believed to support the downregulation of MHC class II transcription factors, stimulation of neurotrophic factors, activation and up-regulation of the IL-4 pathway in CD4+ T cell for anti-inflammatory effects. It also promotes apoptosis in Cytotoxic T-cells (CD8+) and B-cells and also suppresses metabolism in CD14+ and natural killer cells (Thà ¶ne et al., 2016). It is currently undergoing Phase III trials and has resulted in 23% reduction in the rate of relapse of MS while there has been a 37% reduction in contrast enhancing lesions in volunteers (Borrero et al, 2012). Its side effect is only the upregulation of Liver Function Tests (LFTs) The second oral drug that is undergoing phase III clinical trials is Teriflunomide and it is being trialled for patients with RRMS and SPMS. Doses ranging from 7 to 14 mgs daily are recommended to be administered orally in patients. Its mode of action depends on sequestering the production of DNA pyrimidine bases by acting as an inhibitor for the enzyme dihydroorotate dehydrogenase, which is essential in de novo pyrimidine synthesis in T and B cells that are rapidly dividing. This reduces any inflammation that wouldve been caused by those cells and thus immune suppression is achieved. According to Borrero et al, it has a success rate of 61% in reducing contrast enhancing lesions, a rate of 30% in reducing Annualized relapse rates (ARRs) and disability progression was observed to be reduced to 23-30%. Terfilunomidess side effects include Nasopharyngitis; which is the inflammation of the nasopharyngeal duct, diarrhoea, back pain, fatigue, hair thinning, influenza, Urinary Tract Infecti on (UTI), nausea and elevated LFTs (Borrero et al, 2012). The third oral drug is Di-methyl fumarate (DMF) or BG-12. It is also undergoing type III clinical trials for patients with RRMS. Its suggested dose is 120-24 mg three times a day. It has shown a decrease of 69% in contrast enhancing lesions in its phase II trial and its phase III trials have so far showed 53% reduction in ARR, 38% reduction in disability progression and in 2 years, by 49% (Borrero et al, 2012). Di-methyl fumarates mode of action is still being debated but it is believed that it can regulate oxidative pathways which may in turn affect other signalling pathways that are responsible for inducing tissue damage. Studies by Moharregh -Khiabani et al in 2009 showed that DMF had an inhibitory effect on the nuclear factor NFà ºB dependant, TNF à ± induced gene transcription in endothelial cells. It is also believed that DMF can stimulate cells to secrete cytokines such as IL-10, IL-4 and IL_5 which have anti-inflammatory properties thus allowing a more Th2 focused response than a Th1 one (Wierinckx et al., 2005). Moreover, DMF is believed to have a neuroprotective therapeutic effect as well. This occurs as it causes an upregulation in the levels of the detoxification enzyme; NADPH but like other emerging drugs, it has side effects. These side effects include diarrhoea, cramps, elevated LFT, nausea and can cause flushing and in very rare cases, Progressive multifocal leukoencephalopathy (PML) (MS Society 2016). Other novel therapies include the use of monoclonal antibodies (mAb) for the treatment of MS. As of now, there are three that are undergoing phase II and III trials respectively. Alemtuzumab is one such mAb that is in its phase III clinical trial for patients with RRMS and SPMS. Its recommended dosage is Intravenous infusion of 12- 24 mg daily for a course of 5 days every month if its a 1 year course and this can be increased to 24mg on the 12th month. Its mode of action is causing the destruction of circulating immune cells by binding on to CD52 on mature leukocytes which results in the lysis of CD4+ and CD8+ T cells, B cells, eosinophils, NK cells, monocytes and macrophages as well (Hart and Bainbridge 2016). In phase III trials, it has so far shown up to 75% reduction in sustained accumulation disability and up to 74% reduction in relapse rate but has been associated with potentially increasing the risk of autoimmunity which included thyroiditis, idiopathic thrombocytopenic purpur a, autoimmune thyroid-related problems, Goodpastures syndrome and also, can cause flushing and headaches (Borrero et al, 2012) . As of yet, it has not been approved by the FDA as it is still undergoing trials but it is used as a medication for treating a form of blood cancer called B-cell chronic lymphocytic leukaemia (B-CLL) (FDA 2016). References https://www.researchgate.net/profile/Anne_Wierinckx/publication/7750124_Detoxication_enzyme_inducers_modify_cytokine_production_in_rat_mixed_glial_cells/links/0c960534be656953a2000000/Detoxication-enzyme-inducers-modify-cytokine-production-in-rat-mixed-glial-cells.pdf https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2724664/ http://journals.sagepub.com/doi/pdf/10.1177/1756285612450936 https://www.fda.gov/Drugs/DrugSafety/ucm082681.htm http://www.ajmc.com/journals/supplement/2016/cost-effectiveness-multiple-sclerosis/cost-effectiveness-multiple-sclerosis-current-emerging-treatment/P-3 https://www.mssociety.org.uk/what-is-ms/treatments-and-therapies/licensed-disease-modifying-drugs/Tecfidera
Wednesday, October 2, 2019
Powerful Imagery in To His Coy Mistress :: Andrew Marvel, To His Coy Mistress
Andrew Marvel's "To His Coy Mistress" has the persuasiveness of a late night informercial. But in this instance the narrator does not want money for his "product": he wants a girl's virginity. Informercials have an advantage over Marvel. They not only persuade consumers with words but images pf their products as well. Marvell overcomes this obstacle in his use of descriptive imagery. He utilizes if not maximizes imagery to magnify his persuasiveness. . The first stanza opens the poem "Had we but world enough, and time,/ This coyness, Lady, were no crime"(1-2) as though he were a victim of her reserved nature. He tries to pull some reverse psychology here to make her think that it is her fault for not having sex with him (against her will). He goes on to say that he would indeed love her "Till the conversion of the Jews," (10) ithere were time enough, but the narrator never directly says "forever." Instead he uses phrases that conjure images of eternity: "ten years before the Flood(8); "An age to every part"(17). His descriptive use of imagery makes forever seem an overused word that does not fully encapsulate the time he would spend waiting for her. "But" makes the transition from eternity to the present. He continues, "at my back I always hear/ Time's winged chariot hurrying near"(21-22)). Again the narrator makes himself the victim, first of the lady's coyness and now of death. With death soon to knock on his door,, the narrator reminds his mistress of her inevitable death. "They beauty shall no more be found, in they marble vault..."(25-66). They virginity that his mistress is trying to withhold from hom will be lost is she waits too long. Yes. she is at the prime of her youth and beauty today, but it will soon be "turn[ed] to dust"(29)/ This dust and the "deserts of eternity"that lie before them both are used in stark contrast to their ripe youth. This stanza appeals to the girl's immortality and youth. They should both be "like amorous birds of prey" who do not deny their primal instincts. Amorous, meaning eortic, is the pivotal word of this excerpt and one of the most subtly descriptive passages in the entire poem. This words seems to be carefulyy (and craftily) chosen to epitomize the lust he has for this woman; his desire for her to feel the same (or at least act on what she is feelingn). Powerful Imagery in To His Coy Mistress :: Andrew Marvel, To His Coy Mistress Andrew Marvel's "To His Coy Mistress" has the persuasiveness of a late night informercial. But in this instance the narrator does not want money for his "product": he wants a girl's virginity. Informercials have an advantage over Marvel. They not only persuade consumers with words but images pf their products as well. Marvell overcomes this obstacle in his use of descriptive imagery. He utilizes if not maximizes imagery to magnify his persuasiveness. . The first stanza opens the poem "Had we but world enough, and time,/ This coyness, Lady, were no crime"(1-2) as though he were a victim of her reserved nature. He tries to pull some reverse psychology here to make her think that it is her fault for not having sex with him (against her will). He goes on to say that he would indeed love her "Till the conversion of the Jews," (10) ithere were time enough, but the narrator never directly says "forever." Instead he uses phrases that conjure images of eternity: "ten years before the Flood(8); "An age to every part"(17). His descriptive use of imagery makes forever seem an overused word that does not fully encapsulate the time he would spend waiting for her. "But" makes the transition from eternity to the present. He continues, "at my back I always hear/ Time's winged chariot hurrying near"(21-22)). Again the narrator makes himself the victim, first of the lady's coyness and now of death. With death soon to knock on his door,, the narrator reminds his mistress of her inevitable death. "They beauty shall no more be found, in they marble vault..."(25-66). They virginity that his mistress is trying to withhold from hom will be lost is she waits too long. Yes. she is at the prime of her youth and beauty today, but it will soon be "turn[ed] to dust"(29)/ This dust and the "deserts of eternity"that lie before them both are used in stark contrast to their ripe youth. This stanza appeals to the girl's immortality and youth. They should both be "like amorous birds of prey" who do not deny their primal instincts. Amorous, meaning eortic, is the pivotal word of this excerpt and one of the most subtly descriptive passages in the entire poem. This words seems to be carefulyy (and craftily) chosen to epitomize the lust he has for this woman; his desire for her to feel the same (or at least act on what she is feelingn).
Tuesday, October 1, 2019
Frederick Douglass Influence on the Anti-Slavery Movement Essay
Frederick Douglass' Influence on the Anti-Slavery Movement Frederick Douglass was one of the most influential men of the anti-slavery movement. He stood up for what he believed in, fought hard to get where he got and never let someone tell him he could not do something. Frederick Douglass made a change in this country that will always be remembered. Born Frederick Baily, Frederick Douglass was a slave, his birthday is not pin pointed but known to be in February of 1818. He was born on Holmes Hill Farm, near the town of Easton, Maryland. Harriet Baily was Frederick's mother. She worked the cornfields surrounding Holmes Hill. As a boy, he knew little of his father except that the man was white. As a child, he had heard rumors that the master, Aaron Anthony was his father. Frederick's mother was required to work long hours in the fields, so he lived with his grandmother, Betsey Baily. Betsy Baily lived in a cabin a short distance from Holmes Hill Farm. Her job was to look after Harriet's children until they were old enough to work. "Frederick's mother visited him when she could, but he had only a hazy memory of her." He did not think he was a slave during the years with his grandmother. When Frederick was six he was put to work on the Lloyd Plantation. This was the last he saw of his grandmother as he realized that he was now a slave. He learned that the master, Aaron Anthony, would beat his slaves if they did not obey order. Luckily for Frederick he was picked to be Daniel Lloyd's friend, the youngest son of the plantation's owner. Frederick also found a friend in Lucretia Auld, the master's daughter. One day in 1826 Lucretia told Frederick that he was being sent to live with her brother-in-law, Hugh Auld, who managed a ship building company in Baltimore. When Frederick got to the Auld home his only duties were to run errands and care for the Auld's infant son, Tommy. Frederick liked the work and grew to love the child. Sophia Auld was the master's wife, she often read the bible to her son and Frederick. She started to teach Frederick to read and write but soon after the master learned of this and forbid it. Frederick only learned the abhalbit and some words. So he learned the rest by himself. Soon Frederick bought a local paper and learned about abolitionist. This changed his views on many things but was soon sent back to work on a plan... ...ass was given the ceremonial position of marshal for Washington, DC. He enjoyed this post that had a large staff responsible for the overseeing the criminal justice system in Washington D.C. As he got older Douglass settled down doing fewer speeches each year and concentrated on being Marshall. This was until he was appointed to the post of recorder of deeds for Washington, D.C., after the election of 1880. He held the job for 5 years over seeing the department that made records of property sales for the capital. This job left him time to write. He was with his wife until she died in August of 1882. He married again in 1884 to Helen Pitts who was 20 years younger than him. They remained together for 9 years, that was until his sudden death of a heart attack on February 20, 1895. He was 77. Frederick Douglass was laid to rest in Rochester, New York. All of the black public schools closed for the day that he died. Frederick Douglass was a man that touched the hearts of millions and spoke out when no one else would. He fought for the freedom of the black man and stride for the basic human rights they deserved. Frederick Douglass was truly a great man who cried out for freedom.
Breaking a social norms
What Is your paper about? What will you say? Theory: Discuss in detail the theoretical issues that are related to social norms in general and to the one you chose to break in particular. Where do social norms come from? What Is the social norm that you chose and how and why did It evolve? How does your behavior break the social norm? Why is the social norm you broke a social norm? How might normative and Informational social Influence relate to obedience to this arm?Is it a descriptive or an injunctive norm (what are those and why)? What predictions did you have about how you would feel or how people would react? Tell everything you know about social norms and why It relates to the theory. Make sure to address each of these questions at some point in your paper or you will lose Your experience: Describe how your behavior breaks the social norm. What did you do? Describe the reactions of the people when you broke the social norm. Did they get angry?Did they give you weird looks? Did a nyone say anything? Did different types of people react in different ways? Why did they react this way? Did they react how you predicted? You will also want to talk about how you felt. Did you feel embarrassed? Sick to your stomach? Liberated from society? Discuss any reactions or feelings in terms of the relevant theories and studies. It might be also fun to speculate about how someone else might have felt if they were in your position. Integration:How does your experience relate to the theories? Do different theories of conformity predict the reactions you got when you broke the There are many other interesting questions and issues that you might choose to raise when thinking theoretically about the experience of breaking a norm. Conclusion: Take a step back to look at the big picture of social norms. Evaluate your feelings and the behavior you observed in the context of the theories. What does your experience have to add to the theory?
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